Gabapentin(300mg)
Uses
Gabapentin is used to treat fits (epilepsy), long standing pain in legs and/or arms caused by damage to the nerves (peripheral neuropathic pain) and disease of trigeminal nerve (trigeminal neuralgia).
How it works
The exact mechanism of action is unknown; however, gabapentin treats fits (epilepsy by decreasing abnormal excitement in the brain. It also relieves the pain of peripheral neuropathic pain by changing the way the body senses pain.
Dosage
Always follow the instructions of doctor regarding the dosage and duration.
For epilepsy treatment:
Adults and adolescents (12 years and above): 300 mg orally on day one, twice a day on day two, then 3 times a day on day three. (Maximum 1800 mg in 3 divided dose).
Children (6 to 12 years): 10 to 15 mg/kg/day on day one; thereafter 25 to 35 mg/kg/day.
For Peripheral neuropathic pain:
For adults: Initial treatment may be: 300 mg orally on day one, twice a day on day two, then 3 times a day on day three; thereafter 900 to 3600 mg/day.
Common side effects
Very common: Viral infection, sleepiness (somnolence), dizziness, unsteady movements (ataxia), unusual tiredness (fatigue) and fever.
Common: Pneumonia, respiratory infection, inflammation of the air passages (bronchitis), sore throat (pharyngitis), cough, infection of the nose (rhinitis), urinary tract infection, infection, inflammation of ear (otitis media), low white blood cell count (leucopenia), loss of appetite (anorexia), increased appetite, hostility, confusion and emotional liability, depression, anxiety, nervousness, abnormal thoughts,fits (convulsions), increased muscular activity (hyperkinesia), problem with speech (dysarthria), loss of memory (amnesia), uncontrolled shaking (tremor), inability to sleep (insomnia), headache, tingling sensations (paresthesia), excessive sensitivity to touch (hyperesthesia), coordination abnormal, involuntary and rapid repetitive movement of eyes (nystagmus), irregular reflexes, visual disturbances, such as uncorrectable decrease in vision in one or both eyes with no apparent structural abnormality (amblyopia), double vision (diplopia), sensation of rotation (vertigo), high blood pressure (hypertension), increase in the caliber of blood vessels (vasodilatation), breathlessness (dyspnea), vomiting, urge to vomit (nausea), dental abnormalities, inflammation of the gum tissue (gingivitis), loose motions (diarrhea), abdominal pain, indigestion (dyspepsia), constipation, dry mouth or throat, gas (flatulence), facial swelling (edema), purpura most often described as bruises resulting from physical trauma, rash, pruritus, acne, muscle, joint or, bone pain (arthralgia), muscle pain (myalgia), back pain, twitching, impotence, peripheral edema, abnormal gait, weakness (asthenia), pain, malaise, flu syndrome, weight gain, accidental injury, fracture, abrasion.
Uncommon: allergic reactions (pale red, raised, itchy skin rash), generalized swelling (generalized edema), abnormally slow muscle activity (hypokinesia), irregular heartbeats that one can feel (palpitations), elevated liver enzymes and bilirubin.
Who should not take
Gabapentin should not be given to patients who are allergic to the drug or the ingredients used to prepare the tablet or capsule.
Gabapentin should be used with caution in patient who gets fits that begin in one part and then involve the whole of body.Mecobalamin(500mcg)
Uses
To treat low hemoglobin or red blood cells (pernicious and megaloblastic anemia), loss of sensation and pain in extremities (neuropathy). Also used as adjunct therapy in rare conditions that involves severe muscle tightness and decrease in muscle mass (amyotrophic lateral sclerosis).
How it works
Mecobalamin (active form of vitamin B12) assists important enzymes involved in energy production form fats and proteins and synthesis of haemoglobin. It is known to increase production and development of red blood cells by the bone marrow. It assists enzyme methionine synthase which is involved in breakdown of homocysteine thereby reducing its level.
Dosage
Common side effects
It is usually safe when taken orally. Loss of appetite, nausea, vomiting, diarrhea, allergic reactions (skin rashes), itching and other injection site related side effects (pain and blood clots) may occur.
Who should not take
Hypersensitivity.
Gabapentin(300mg)
Uses
Gabapentin is used to treat fits (epilepsy), long standing pain in legs and/or arms caused by damage to the nerves (peripheral neuropathic pain) and disease of trigeminal nerve (trigeminal neuralgia).
How it works
The exact mechanism of action is unknown; however, gabapentin treats fits (epilepsy by decreasing abnormal excitement in the brain. It also relieves the pain of peripheral neuropathic pain by changing the way the body senses pain.
Dosage
Always follow the instructions of doctor regarding the dosage and duration.
For epilepsy treatment:
Adults and adolescents (12 years and above): 300 mg orally on day one, twice a day on day two, then 3 times a day on day three. (Maximum 1800 mg in 3 divided dose).
Children (6 to 12 years): 10 to 15 mg/kg/day on day one; thereafter 25 to 35 mg/kg/day.
For Peripheral neuropathic pain:
For adults: Initial treatment may be: 300 mg orally on day one, twice a day on day two, then 3 times a day on day three; thereafter 900 to 3600 mg/day.
Common side effects
Very common: Viral infection, sleepiness (somnolence), dizziness, unsteady movements (ataxia), unusual tiredness (fatigue) and fever.
Common: Pneumonia, respiratory infection, inflammation of the air passages (bronchitis), sore throat (pharyngitis), cough, infection of the nose (rhinitis), urinary tract infection, infection, inflammation of ear (otitis media), low white blood cell count (leucopenia), loss of appetite (anorexia), increased appetite, hostility, confusion and emotional liability, depression, anxiety, nervousness, abnormal thoughts,fits (convulsions), increased muscular activity (hyperkinesia), problem with speech (dysarthria), loss of memory (amnesia), uncontrolled shaking (tremor), inability to sleep (insomnia), headache, tingling sensations (paresthesia), excessive sensitivity to touch (hyperesthesia), coordination abnormal, involuntary and rapid repetitive movement of eyes (nystagmus), irregular reflexes, visual disturbances, such as uncorrectable decrease in vision in one or both eyes with no apparent structural abnormality (amblyopia), double vision (diplopia), sensation of rotation (vertigo), high blood pressure (hypertension), increase in the caliber of blood vessels (vasodilatation), breathlessness (dyspnea), vomiting, urge to vomit (nausea), dental abnormalities, inflammation of the gum tissue (gingivitis), loose motions (diarrhea), abdominal pain, indigestion (dyspepsia), constipation, dry mouth or throat, gas (flatulence), facial swelling (edema), purpura most often described as bruises resulting from physical trauma, rash, pruritus, acne, muscle, joint or, bone pain (arthralgia), muscle pain (myalgia), back pain, twitching, impotence, peripheral edema, abnormal gait, weakness (asthenia), pain, malaise, flu syndrome, weight gain, accidental injury, fracture, abrasion.
Uncommon: allergic reactions (pale red, raised, itchy skin rash), generalized swelling (generalized edema), abnormally slow muscle activity (hypokinesia), irregular heartbeats that one can feel (palpitations), elevated liver enzymes and bilirubin.
Who should not take
Gabapentin should not be given to patients who are allergic to the drug or the ingredients used to prepare the tablet or capsule.
Gabapentin should be used with caution in patient who gets fits that begin in one part and then involve the whole of body.Mecobalamin(500mcg)
Uses
To treat low hemoglobin or red blood cells (pernicious and megaloblastic anemia), loss of sensation and pain in extremities (neuropathy). Also used as adjunct therapy in rare conditions that involves severe muscle tightness and decrease in muscle mass (amyotrophic lateral sclerosis).
How it works
Mecobalamin (active form of vitamin B12) assists important enzymes involved in energy production form fats and proteins and synthesis of haemoglobin. It is known to increase production and development of red blood cells by the bone marrow. It assists enzyme methionine synthase which is involved in breakdown of homocysteine thereby reducing its level.
Dosage
Common side effects
It is usually safe when taken orally. Loss of appetite, nausea, vomiting, diarrhea, allergic reactions (skin rashes), itching and other injection site related side effects (pain and blood clots) may occur.
Who should not take
Hypersensitivity.
