Glibenclamide is used to lower the blood sugar level in patients with type 2 diabetes mellitus that is not controlled by diet and exercise alone.
How it works
Glibenclamide also known as glyburide is one of a group of medicines called sulphonylurea and it acts by promoting insulin secretion in the body, so that the blood sugars are utilized by various organs, leading to a fall in blood levels of sugar.
Dosage
Always follow the instructions of doctor regarding the dosage and duration.
Treatment of type 2 diabetes;
In adult patient: start with 5 mg once daily with or immediately after breakfast (maximum 15 mg daily).
In elderly or debilitated patient: start with 2.5 mg once daily, with further dose as adjusted by your doctor according to response (maximum 15 mg daily).
Common side effects
Low blood sugar, nausea, vomiting, heartburn, loss of appetite, diarrhea, metallic taste, increased appetite and weight gain, skin rashes (usually allergic reactions), photosensitivity, severe manifestations of allergy including cholestatic jaundice (yellowness of eyes and skin due to obstruction to flow of bile from liver), abnormal blood counts, hemolytic anemia, erythema multiforme, Stevens-Johnson syndrome (serious, widespread, allergic reaction with a rash involving the skin and internal lining of the skin, exfoliative dermatitis and erythema nodosum, inappropriate antidiuretic hormone secretion.
Who should not take
Patients allergic to glibenclamide, or any of the excipients, other sulphonylurea, and sulphonamides. Glibenclamide is not recommended; for use in children, adolescents and elderly (over 70 years of age).
if you have type 1 diabetes.
if you have or ever had ketone bodies and sugar in your urine (diabetic ketoacidosis).
if you suffer from severe impairment of kidney, liver, thyroid or adrenocorticoid function.
in case of recent surgery, severe infection, stress or trauma.
if you have porphyria (a disease of blood proteins affecting the skin, gut and nervous system).
if you are suffering from G6PD deficiency (a disease that causes abnormal destruction of your red blood cells).
if you are pregnant or nursing. Metformin(500mg)
Uses
Metformin is an antidiabetic medicine that helps to control blood sugar in people with type 2 diabetes mellitus.
How it works
Metformin belongs to class of medications called antidiabetics.It decreases the amount of glucose absorbed from the food and the amount ofglucose made by liver. Metformin also increases the body's response to insulin(a natural substance that controls the amount of glucose in the blood).
Dosage
Adults: 500 mg or 850 mg 2 or 3 times daily given during or after meals to maximum of 3 g daily, taken as 3 divided doses.
Children (from 10 years of age and adolescents): 500 mg or 850 mg once daily, given during or after meals to maximum of 2 g daily, taken as 2 or 3 divided doses.
Common side effects
Nausea, vomiting, diarrhea, abdominal pain and loss of appetite, taste disturbance, Lactic acidosis (symptoms are vomiting, abdominal pain with muscle cramps, not feeling well with severe tiredness, and difficulty in breathing), malabsorption of vitamin B12, skin reactions.
Who should not take
Patients with serious complication of diabetes where high levels of blood acids called ketones are produced in the body (diabetic ketoacidosis); diabetic pre-coma; patients with kidney problem, liver problem, or heart failure; alcoholism.
Glibenclamide is used to lower the blood sugar level in patients with type 2 diabetes mellitus that is not controlled by diet and exercise alone.
How it works
Glibenclamide also known as glyburide is one of a group of medicines called sulphonylurea and it acts by promoting insulin secretion in the body, so that the blood sugars are utilized by various organs, leading to a fall in blood levels of sugar.
Dosage
Always follow the instructions of doctor regarding the dosage and duration.
Treatment of type 2 diabetes;
In adult patient: start with 5 mg once daily with or immediately after breakfast (maximum 15 mg daily).
In elderly or debilitated patient: start with 2.5 mg once daily, with further dose as adjusted by your doctor according to response (maximum 15 mg daily).
Common side effects
Low blood sugar, nausea, vomiting, heartburn, loss of appetite, diarrhea, metallic taste, increased appetite and weight gain, skin rashes (usually allergic reactions), photosensitivity, severe manifestations of allergy including cholestatic jaundice (yellowness of eyes and skin due to obstruction to flow of bile from liver), abnormal blood counts, hemolytic anemia, erythema multiforme, Stevens-Johnson syndrome (serious, widespread, allergic reaction with a rash involving the skin and internal lining of the skin, exfoliative dermatitis and erythema nodosum, inappropriate antidiuretic hormone secretion.
Who should not take
Patients allergic to glibenclamide, or any of the excipients, other sulphonylurea, and sulphonamides. Glibenclamide is not recommended; for use in children, adolescents and elderly (over 70 years of age).
if you have type 1 diabetes.
if you have or ever had ketone bodies and sugar in your urine (diabetic ketoacidosis).
if you suffer from severe impairment of kidney, liver, thyroid or adrenocorticoid function.
in case of recent surgery, severe infection, stress or trauma.
if you have porphyria (a disease of blood proteins affecting the skin, gut and nervous system).
if you are suffering from G6PD deficiency (a disease that causes abnormal destruction of your red blood cells).
if you are pregnant or nursing. Metformin(500mg)
Uses
Metformin is an antidiabetic medicine that helps to control blood sugar in people with type 2 diabetes mellitus.
How it works
Metformin belongs to class of medications called antidiabetics.It decreases the amount of glucose absorbed from the food and the amount ofglucose made by liver. Metformin also increases the body's response to insulin(a natural substance that controls the amount of glucose in the blood).
Dosage
Adults: 500 mg or 850 mg 2 or 3 times daily given during or after meals to maximum of 3 g daily, taken as 3 divided doses.
Children (from 10 years of age and adolescents): 500 mg or 850 mg once daily, given during or after meals to maximum of 2 g daily, taken as 2 or 3 divided doses.
Common side effects
Nausea, vomiting, diarrhea, abdominal pain and loss of appetite, taste disturbance, Lactic acidosis (symptoms are vomiting, abdominal pain with muscle cramps, not feeling well with severe tiredness, and difficulty in breathing), malabsorption of vitamin B12, skin reactions.
Who should not take
Patients with serious complication of diabetes where high levels of blood acids called ketones are produced in the body (diabetic ketoacidosis); diabetic pre-coma; patients with kidney problem, liver problem, or heart failure; alcoholism.