Miconazole is an imidazole (organic compound) antifungal agent used to treat fungal and associated bacterial super infections of the skin and nails Miconazole is also used for oral treatment and prevention of fungal infections of the mouth, throat and food pipe Miconazole is effectively used in vulvovaginal (vagina and external genital organs) candidiasis (thrush) and other yeast infection of the vagina. Further, Miconazole is also prescribed for napkin rash and inflammation of the folds of tissue surrounding the nails of toes or fingers (paronychia).
How it works
Miconazole acts mainly by preventing the growth of fungi. It interacts with chemicals (cytochrome P-450) inside the fungus and prevents the synthesis of an essential component of fungal cell membrane (ergosterol); this results in increased cellular permeability causing leakage of cellular contents from fungal cell, ultimately preventing fungal growth. Miconazole possesses antifungal activity against dermatophytes and yeasts as well as antibacterial activity against certain gram-positive bacilli and cocci.
Dosage
Always follow the instructions of doctor regarding the dosage and duration.
Fungal infection of the mouth throat and food pipe (oropharyngeal candidiasis):
Adults and Children 2 years and above: 2.5 ml (50 mg/ one-half spoon) once daily for 14 days, or 2 % gel applied four times a day after meals.
Infants (4-24 months): 1.25 ml (25 mg/ one-fourth spoon) gel applied four times a day after meals.
Vulvovaginal (vagina and external genital organs) yeast infections:
Adults: 1200 mg vaginal insert to be placed using an applicator at bedtime, as directed by your doctor.
Skin infections and nail infections:
Creams (10-15 g) to be applied twice daily for at least 10 days.
Tinea manus, Tinea pedis, Tinea cruris, Tinea corporis and Tinea capitis (fungal infection of the hand, foot, skin ringworm, and scalp ringworm, respectively).
Creams (10-15 g/ 2%) to be applied twice daily for 2-6 weeks, treatment should be continued at least one week after disappearance of all signs and symptom.
Common side effects
Headache, pain in the abdomen, nausea, diarrhea, change in taste, rash, genital itching in females, vaginal burning sensation, vulvovaginal (vagina and external genital organs) discomfort,itching of skin), pain during periods, redness of skin, application site irritation, application site burning, application site warmth, application site itchiness, skin inflammation, skin discoloration.
Who should not take
Miconazole is contraindicated in patients with kidney or liver problems.
Patients who have known allergy to miconazole or any the ingredients of the capsule/gel, or to any other antifungal medicines.
Oral preparation (to treat oropharynx) like gel is contraindicated in infants less than 4 months of age or in those whose swallowing reflex is not sufficiently developed. Acne vulgaris, skin infections with susceptible bacteria.
How it works
Nadifloxacin inhibits the enzyme DNA gyrase that is involved in bacterial DNA synthesis and replication, thus inhibiting the bacterial multiplication.
Common side effects
Itching, irritation, redness, flushes, papules, feeling of warmth, increased sweating, contact dermatitis and dryness of the skin.
Who should not take
Hypersensitivity.
Mometasone(Mg)
Uses
Mometasone is used to treat used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. It is also used to relieve symptoms of hay fever, allergies of nose and nasal polyps (fleshy swelling inside the nose).
How it works
Mometasone belongs to a category of drugs called as corticosteroids. It works by reducing the production of substances in the body that cause inflammation and allergies.
Dosage
Always follow the instructions of doctor regarding the dosage and duration.
Dermatoses in adults: 0.1% cream or ointment or lotion.
Allergic rhinitis in adults: 100 ?g in each nostril once. Usual maintenance dose 50 ?g in each nostril daily.
Asthma:
Adults: 200-400 ?g daily in 1-2 divided doses.
Children (more than 6 years of age): 100 ?g once daily.
Common side effects
Headache, burning, itching or thinning of the skin, lightening of skin, acne, pimples, spots on the skin and dry mouth, sore throat, nose bleeds, increased hair growth on face, hands, back.
Who should not take
Mometasone should not be taken:
If the patient is allergic to it or to any other content in the medicine.
If you have had an infection or injury or surgical procedure of the nose.
If the patient is a child less than 6 years of age.
Miconazole is an imidazole (organic compound) antifungal agent used to treat fungal and associated bacterial super infections of the skin and nails Miconazole is also used for oral treatment and prevention of fungal infections of the mouth, throat and food pipe Miconazole is effectively used in vulvovaginal (vagina and external genital organs) candidiasis (thrush) and other yeast infection of the vagina. Further, Miconazole is also prescribed for napkin rash and inflammation of the folds of tissue surrounding the nails of toes or fingers (paronychia).
How it works
Miconazole acts mainly by preventing the growth of fungi. It interacts with chemicals (cytochrome P-450) inside the fungus and prevents the synthesis of an essential component of fungal cell membrane (ergosterol); this results in increased cellular permeability causing leakage of cellular contents from fungal cell, ultimately preventing fungal growth. Miconazole possesses antifungal activity against dermatophytes and yeasts as well as antibacterial activity against certain gram-positive bacilli and cocci.
Dosage
Always follow the instructions of doctor regarding the dosage and duration.
Fungal infection of the mouth throat and food pipe (oropharyngeal candidiasis):
Adults and Children 2 years and above: 2.5 ml (50 mg/ one-half spoon) once daily for 14 days, or 2 % gel applied four times a day after meals.
Infants (4-24 months): 1.25 ml (25 mg/ one-fourth spoon) gel applied four times a day after meals.
Vulvovaginal (vagina and external genital organs) yeast infections:
Adults: 1200 mg vaginal insert to be placed using an applicator at bedtime, as directed by your doctor.
Skin infections and nail infections:
Creams (10-15 g) to be applied twice daily for at least 10 days.
Tinea manus, Tinea pedis, Tinea cruris, Tinea corporis and Tinea capitis (fungal infection of the hand, foot, skin ringworm, and scalp ringworm, respectively).
Creams (10-15 g/ 2%) to be applied twice daily for 2-6 weeks, treatment should be continued at least one week after disappearance of all signs and symptom.
Common side effects
Headache, pain in the abdomen, nausea, diarrhea, change in taste, rash, genital itching in females, vaginal burning sensation, vulvovaginal (vagina and external genital organs) discomfort,itching of skin), pain during periods, redness of skin, application site irritation, application site burning, application site warmth, application site itchiness, skin inflammation, skin discoloration.
Who should not take
Miconazole is contraindicated in patients with kidney or liver problems.
Patients who have known allergy to miconazole or any the ingredients of the capsule/gel, or to any other antifungal medicines.
Oral preparation (to treat oropharynx) like gel is contraindicated in infants less than 4 months of age or in those whose swallowing reflex is not sufficiently developed. Acne vulgaris, skin infections with susceptible bacteria.
How it works
Nadifloxacin inhibits the enzyme DNA gyrase that is involved in bacterial DNA synthesis and replication, thus inhibiting the bacterial multiplication.
Common side effects
Itching, irritation, redness, flushes, papules, feeling of warmth, increased sweating, contact dermatitis and dryness of the skin.
Who should not take
Hypersensitivity.
Mometasone(Mg)
Uses
Mometasone is used to treat used to treat the inflammation and itching caused by a number of skin conditions such as allergic reactions, eczema, and psoriasis. It is also used to relieve symptoms of hay fever, allergies of nose and nasal polyps (fleshy swelling inside the nose).
How it works
Mometasone belongs to a category of drugs called as corticosteroids. It works by reducing the production of substances in the body that cause inflammation and allergies.
Dosage
Always follow the instructions of doctor regarding the dosage and duration.
Dermatoses in adults: 0.1% cream or ointment or lotion.
Allergic rhinitis in adults: 100 ?g in each nostril once. Usual maintenance dose 50 ?g in each nostril daily.
Asthma:
Adults: 200-400 ?g daily in 1-2 divided doses.
Children (more than 6 years of age): 100 ?g once daily.
Common side effects
Headache, burning, itching or thinning of the skin, lightening of skin, acne, pimples, spots on the skin and dry mouth, sore throat, nose bleeds, increased hair growth on face, hands, back.
Who should not take
Mometasone should not be taken:
If the patient is allergic to it or to any other content in the medicine.
If you have had an infection or injury or surgical procedure of the nose.
If the patient is a child less than 6 years of age.